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The toxicity was most likely as a result of formation of highly poisonous phosphine gasoline rather than to Al exposure (Alter et al., 2001; Kamanyire and Murray, 2003; Moghadamnia, 2012). However, Hasseeb et al. reported neutrophilic and mononuclear cell infiltrations of lung alveoli of rats administered 37 mg/kg/day of Al chloride in consuming water for eight weeks. Congested blood vessels in inter-alveolar areas had been reported after administration of various concentrations of Al chloride via gavage for eight weeks . Pulmonary lesions are uncommon and inconsistent in experimental animals where Al exposure isn't via aerosol automobiles. Under natural situations, the vehicular substances and the Al speciation may affect the stimulation of continual pathologic reactions in the lung. The preliminary aim in our research group was to explore the position of the ever-present Al ion in erythrocyte membrane dysfunction and metabolic dysregulation .